Clinical Chemistry Blog Note 02

DUTY!

2010-01-08T05:36:00.000-08:00

nakakapagod magduty,

lalu na kapag busy.

marami nanaman ang mga opd,

toxic nanaman ang clinical chemistry.

ang panget ng blood smear ko,

maam paturo naman ng technique mo.

may t. vaginalis ang urine nya,

susulat ko iyan sa quota ko para masaya,

ang saya mag cross match sa diamed,

kaysa sa mag embed.

huwag kakalimutan ang thio,

baka mademerit tayo.

kukuha na pu ako ng dugo,

sandali anu po kasi pangalan ninyo?

may record napuba kayo?

kung wala, paki sagutan nalang po ito.

pasahod daw sa E.R.

pa RBS narin daw.

may blood donor nanaman,

sa wakas, makakatusok nanaman.

AB pasitib daw ang blood type niya,

wow, royal blood siya.

ang saya talaga magduty,

kahit nakakapagod parati.

pag-uwi ko, knock out ako nito.

pero ayus lang, masayang experience nanaman to.

tatlung buwan nalang matatapos kana,

kaya lulubusin kuna.

salamat sa pagbabasa,

comment nalang pagkatapos tumawa.

Do you agree that drug testing should be done as a requirement for admission to schools?

2009-09-01T06:21:00.000-07:00

MARIJUANA, BATO, ECSTACY, COCAINE. They will make you insane.

I agree that drug testing should be done as a requirement for the admission to schools. So that the students who are in addiction will be afraid to enter the school, because they will not be accepted.

Basically drug addiction is one of the main problems of our country. Many lives have been destroyed because of drugs. I think this is one way to stop it to protect students' lives, and not just to perform drug testing. The school must educate the students too on how to prevent the use or how to stop them from using these types of drugs. Of course students would not like to have a classmate who is an ADDICT, right? That would be scary!

"YES TO SCHOOLING

NO TO DRUG TAKING"

Are your TARGET's CORRECT?

2009-08-30T21:54:00.000-07:00

1. Receptor

2. Target Cells

3. Anterior pituitary gland

4. Thyroid gland

5. Reproductive organs

6. Bone, kidney, GI tract

7. Reproductive organs

8. Adrenal cortex

9-10. Steroid hormone receptors and Peptide hormone receptors

Case Analysis:

Target cell responds to the hormone to perform the hormones mechanism, it triggers the hormones action. Hormone receptors are found either the surface or inside of the cell. Binding of hormone to the receptor initiates the reaction.

Did You Find your TARGET?

2009-08-25T19:09:00.000-07:00

1. It triggers the action of hormone in a target cell.

2. They are the receptors of the hormones.

3. The target cell of the TRH.

4. The target cell of TSH.

5. The target cell of LH.

6. The target cell of Calcitonin.

7. The target cell of FSH.

8. The target cell of Antidiuretic hormone.

9-10. two types of cell receptors.

Case Analysis:

Discuss the mechanism of action of the target cell.

TARGET CELLS

2009-08-18T01:53:00.000-07:00

Target cells are the receptors of the hormone. Hormones have a specific target cell. It responds to the hormone because it has receptors for the hormone. Hormone receptors are found either the surface or inside of the cell.

Binding of hormone to the receptor initiates the reaction. The TRH target cell is located in the cytoplasm intra-cellularly. In order to bind to the specific receptor the hormone has to travel to the membrane of the cell and bind to the DNA.

Top 10 Influential Blogs

2009-07-28T01:27:00.000-07:00

Here are my nominees for Top 10 Emerging Influential Blogs of 2009:

1. Roy The Struggling Blogger
2. Doctor Z of Zorlone
3. Jan Geronimo of WritingToExhale
4. Angel Cuala of Father Blogger dot com
5. Irene of LifeLots
6. Luke of A Walk In The Dark
7. Holly Jahangiri of It’s all a matter of Perspective: Mine
8. Bingkee of I Love/Hate America
9. Kelvin Servigon of Kelvinonian Ideas 2.0
10. Dee of Tales From The Mom Side

I nominated these blogs because they catch my attention. Reading them will make you be a good blogger especially if you are a beginner just like me, hihihi. you will get new and brighter techniques on your post. Thank you for your wonderful post i really love them a lot. =)

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I NEVER THOUGHT

2009-07-14T01:12:00.000-07:00

I never thought
I will write this thought
But I have no choice
But to publish this post

Hypothalamus produces the hormone
Thyrotropin Releasing Hormone
Responsible for the regulation of the hormone-
Thyrotropin Stimulating Hormone

These hormones work together
To make your body stronger
They love one other
and act as stabilizers.

If there is increase in TRH
There will be high TSH
If there is decrease in TRH
There will be low TSH

TRH stimulation Test
is uses to monitor patients
With hyperthyroidism
And hypothyroidism

If there is exaggerated response -
It is Primary Hypothyroidism
If there is no response -
It is Primary Hyperthyroidism

Do you have a goiter?
Or have finger tremors?
Maybe some coarse hair?
Or loss of eyebrow hair?

If TRH does not function well
Your life will be in hell
Cause you are unlucky
And you will be ugly

This is what I got;
I hope you're not mad
Coz this is all the lot
Hoping your comment's won't be bad.

2009-06-29T16:14:00.000-07:00

Answers:
I.

1. Thyrotropin Releasing Hormone
2. Thyrotropin Releasing Hormone Stimulation Test
3. Hypothalamus
4. TRH
5. Anterior Pituitary
6. Hyperthyroidism
7. Hypothalamus
8. Thyrotropin Releasing Factor (TRF), thyroliberin or protilerin
9. Thyrotropin Releasing Factor
10. Thyrotropin Releasing Hormone Stimulation Test

II.

1. The casuse of the disease is lack of iodine, and this causes Goiter also called Bronchocele. The patient may be given an iodine supplement orally. This may lead to goiter reduction size. And by surgical removal.

TRH QUIZ

2009-06-16T19:47:00.001-07:00

__________1. Transcribe TRH.
__________2. It is the test for TRH.
__________3. Endorine gland that releases TRH.
__________4. Its Function is to control TSH production.
__________5. Endocrine gland that releases TSH.
__________6. Increase stimulation of TRH may cause this disease.
__________7. Regulates the TRH production.
__________8. Other name of TRH.
__________9. Transcribe TRF.
__________10. It is the confirmatory test for primary hyperthyroidism.

11-20

A 30 year old woman, has an enlarge neck and protruding eyes. She reported about swallowing difficulties from compression of the esophagus, neck vein distention and dizziness when the arms are raised above the head. She tested for iodine test and the doctor's found out that she lacks of iodine.

What is the probable cause of the disease? What methods can be done to treat this disease?

Thyrotropin Releasing Hormone (TRH)

2009-06-02T03:15:00.000-07:00

Thyrotropin Releasing Hormone (TRH) also called Thyrotropin Releasing Factor (TRF), thyroliberin or protilerin. Its function is to control the release of thyroid stimulating hormone (TSH) which produces thyroid hormones responsible for the growth of thyroid gland by the anterior pituitary.

Thyrotropin Releasing Hormone Stimulation Test

It is use to monitor patients who have hyperthyroidism or hypothyroidism. it is use to detect residual TSH stores in the pituitary gland

. It is the confirmatory test for primary hyperthyroidism. it is also use to detect thyroid hormone resistance syndromes. it can differentiate secondary hypothyroidism from tertiary hypothyroidism. WheN a TRH is injected on a patient with secondary hypothyroidism, the TSH level will not increase but when TRH is injected with patient that suffers with tertiary hypothyroidism it will respond to TRH stimulation.

Specimen:
Red Tap or EDTA
Intravenous 200 – 500 ug of synthetic TRH
specimen free from lipemia and hemolysis

Procedure:

>The test is performed in the morning, with a overnight fasting.

>Samples for TSH are drawn before 30 minutes and 60 minutes before the administration of TRH.

>TRH is injected intravenously.

Side Effects And Risks:

It may cause nausea, vomiting and urge to urinate. It may also cause constriction of the blood vessel which can lead to hemorrhage in patients with pre existing pituitary tumors.

Reference:

http://www.clinlabnavigator.com/Tests/ThyrotropinRelHormoneStimTest.html

http://en.wikipedia.org/wiki/Thyrotropin-releasing_hormone

Clinical Chemistry Principles, Procedures, Correlations
by: Michael L. Bishop, Janet L. Duben-Engelkirk and Edward P. Fody